SCHEMBL63724

SCHEMBL63724

COCc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.56
ESR1 P03372 5/20 0.52
ESR2 Q92731 2/20 0.52
CALM1 P0DP23 1/20 0.50
ABAT P80404 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CA2 P00918 2/20 0.46
APP P05067 1/20 0.45
TAAR1 Q96RJ0 3/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
SLC6A2 P23975 3/20 0.44
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 1/20 0.44
CA12 O43570 1/20 0.44
GMNN O75496 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL4440182 0.89 IDO1 (0.46) IDO1ESR1ESR2CALM1ABAT
SCHEMBL134443 0.88 IDO1 (0.46) IDO1APPLMNATP53
SCHEMBL9856469 0.87 APP (0.54) ESR1MEN1KMT2ACA2APP
SCHEMBL9856466 0.87 APP (0.54) ESR1MEN1KMT2ACA2APP
SCHEMBL6678216 0.81 TSHR (0.43) IDO1CA2LMNACA12CA1
SCHEMBL3150955 0.81 TSHR (0.43) IDO1CA2LMNACA12CA1
SCHEMBL15452321 0.80 IDO1 (0.48) IDO1ESR1ESR2CALM1ABAT
SCHEMBL8020885 0.80 ESR1 (0.48) IDO1ESR1ESR2CALM1KMT2A
SCHEMBL9679767 0.80 TSHR (0.52) IDO1CA2APPLMNACA1
SCHEMBL11310162 0.80 ESR1 (0.48) IDO1ESR1ESR2CALM1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419532-A1 FUSED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS NLRP3 INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-08-28 EP claimed
CN-118206753-A Photosensitive polyimide polymer, photosensitive polyimide resin composition, application of photosensitive polyimide resin composition and preparation method of pattern cured film 徐州博康信息化学品有限公司 2024-06-18 CN claimed
CN-114524938-B Polymer, photosensitive resin composition, cured film prepared from polymer and photosensitive resin composition, and electronic element 江苏三月科技股份有限公司 2024-02-09 CN claimed
CN-117247517-A Benzoxazine resin-based macromolecular surfactant and preparation method and application thereof 衡水学院 2023-12-19 CN claimed
CN-116574561-A Essence for vanilla special-color cigarettes and application of essence in cigarettes 中国烟草总公司郑州烟草研究院 2023-08-11 CN claimed
EP-4188589-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-06-07 EP claimed
CN-116217350-A Preparation method of p-hydroxybenzyl methyl ether 昆明理工大学 2023-06-06 CN claimed
US-20230148641-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2023-05-18 US claimed
WO-2023066825-A1 FUSED BICYCLIC HETEROARYL COMPOUNDS USEFUL AS NLRP3 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2023-04-27 WO claimed
CN-115975551-A Transparent butyl hot melt adhesive and preparation method thereof 郑州中原思蓝德高科股份有限公司 2023-04-18 CN claimed
WO-2015048268-A1 SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS WILLIAM MARSH RICE UNIVERSITY (US) 2015-04-02 WO claimed
CN-102351657-B Method for preparing 1,3,5-trimethyl-2,4,6-tris(3,5-di-tert-butyl-4-hydroxybenzyl) benzene XINJIANG TECH INST PHYSICS CAS 2013-10-16 CN claimed
EP-1702919-B1 NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE MSD KK (JP) 2012-05-30 EP claimed
US-20110177454-A1 RESIST MATERIAL AND PATTERN FORMATION METHOD USING THE RESIST MATERIAL PANASONIC CORPORATION (JP) 2011-07-21 US claimed
US-7799508-B2 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and process for manufacturing the same FUJITSU LIMITED (JP) 2010-09-21 US claimed
US-20090226844-A1 Resist pattern thickening material and process for forming resist pattern,and semiconductor device and process for manufacturing the same FUJITSU LIMITED (JP) 2009-09-10 US claimed
US-7425643-B1 Electron acceptors for nonlinear optical chromophores UNIVERSITY OF WASHINGTON (US) 2008-09-16 US claimed
EP-1392673-A2 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2004-03-03 EP claimed
WO-2002096901-A2 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-12-05 WO claimed
US-5563176-A Illudin analogs useful as antitumor agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-10-08 US claimed