SCHEMBL637359

SCHEMBL637359

Cc1ccccc1-c1nc2nc(N)[nH]c(=O)c2[nH]1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 6/20 0.73
FGFR2 P21802 6/20 0.73
PNP P00491 6/20 0.56
FGFR3 P22607 1/20 0.54
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
THRB P10828 1/20 0.49
HPGD P15428 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7875967 0.87 FGFR1 (0.69) FGFR1FGFR2PNPFGFR3KDM4E
SCHEMBL1286954 0.83 FGFR1 (0.67) FGFR1FGFR2PNPFGFR3KDM4E
SCHEMBL1286943 0.80 FGFR1 (1.00) FGFR1FGFR2PNPMEN1ALDH1A1
SCHEMBL3740382 0.79 FGFR1 (0.55) FGFR1FGFR2PNPMEN1KMT2A
SCHEMBL8141955 0.78 FGFR1 (0.53) FGFR1FGFR2PNPFGFR3
SCHEMBL1553507 0.77 FGFR1 (0.52) FGFR1FGFR2FGFR3KDM4EMEN1
SCHEMBL9434929 0.75 PNP (0.71) FGFR1FGFR2PNP
SCHEMBL1286938 0.74 FGFR1 (0.72) FGFR1FGFR2PNPFGFR3KDM4E
SCHEMBL11610791 0.73 FGFR1 (0.62) FGFR1FGFR2PNPFGFR3KDM4E
8-Aminoguanine SCHEMBL21761 0.73 PNP (1.00) FGFR1FGFR2PNPKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118203522-A Sugar-resistant, oxidation-resistant and aging-resistant compound and preparation method and application thereof 上海肤徕生物高科技有限公司 2024-06-18 CN claimed
CN-118203522-A Sugar-resistant, oxidation-resistant and aging-resistant compound and preparation method and application thereof 上海肤徕生物高科技有限公司 2024-06-18 CN disclosed
EP-2990438-B1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION, AND CROSSLINKED RUBBER PRODUCT ZEON CORP (JP) 2020-04-01 EP disclosed
US-20160090464-A1 NITRILE RUBBER COMPOSITION, CROSS-LINKABLE RUBBER COMPOSITION, AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2016-03-31 US disclosed
EP-2990438-A1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION, AND CROSSLINKED RUBBER PRODUCT Zeon Corporation (JP) 2016-03-02 EP disclosed
US-8642718-B2 Curable composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-02-04 US disclosed
EP-1882713-B1 CURABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2013-07-03 EP disclosed
EP-1775315-B1 POLYMERIZABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2012-02-22 EP disclosed
CN-101175792-B Curable composition MITSUBISHI GAS CHEMICAL CO 2011-01-26 CN disclosed
EP-1398317-B1 ALICYCLIC COMPOUND FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2011-01-12 EP disclosed
US-7091307-B2 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-08-15 US disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040158031-A1 Alicyclic compound for optical material MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-08-12 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
US-20040122201-A1 polysulfides; improved impact resistance MITSUBISHI GAS CHEMICAL COMPANY (JP) 2004-06-24 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed
EP-1398317-A1 ALICYCLIC COMPOUND FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-03-17 EP disclosed
EP-1326095-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-07-09 EP disclosed
EP-1319966-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-06-18 EP disclosed
US-4877817-A BLEND WITH A MERCAPTOTRIAZINE COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-10-31 US disclosed