Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.66 |
| ▸ | ESRRA | P11474 | 7/20 | 0.59 |
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373692 | 1.00 | CSNK2A1 (0.66) | CSNK2A1ESRRAEGFRERBB2CSNK2A2 | |
| SCHEMBL6378603 | 0.91 | CSNK2A1 (0.77) | CSNK2A1ESRRAEGFRERBB2CSNK2A2 | |
| SCHEMBL6378608 | 0.91 | CSNK2A1 (0.77) | CSNK2A1ESRRAEGFRERBB2CSNK2A2 | |
| SCHEMBL6375707 | 0.89 | ESRRA (0.69) | CSNK2A1ESRRAEGFRCSNK2A2CSNK2B | |
| SCHEMBL6372526 | 0.89 | CSNK2A1 (0.77) | CSNK2A1ESRRACSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6372523 | 0.89 | CSNK2A1 (0.77) | CSNK2A1ESRRACSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6375704 | 0.89 | ESRRA (0.69) | CSNK2A1ESRRAEGFRCSNK2A2CSNK2B | |
| SCHEMBL6375659 | 0.88 | ESRRA (0.59) | CSNK2A1ESRRACSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6375661 | 0.88 | ESRRA (0.59) | CSNK2A1ESRRACSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL6373841 | 0.87 | CSNK2A1 (0.78) | CSNK2A1ESRRACSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | claimed |
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |