⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377749 | 0.92 | — | — | |
| SCHEMBL6377549 | 0.89 | — | — | |
| SCHEMBL29615158 | 0.86 | TRPV1 (0.76) | — | |
| SCHEMBL6377282 | 0.86 | TRPV1 (0.76) | — | |
| SCHEMBL6081133 | 0.83 | — | — | |
| SCHEMBL93984 | 0.81 | — | — | |
| SCHEMBL29454692 | 0.81 | — | — | |
| SCHEMBL29383168 | 0.81 | — | — | |
| SCHEMBL6377503 | 0.79 | TRPV1 (0.76) | — | |
| SCHEMBL6301844 | 0.79 | TRPV1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154989-B1 | VANILLOID ANALOGUES CONTAINING RESINIFERATOXIN PHARMACOPHORES AS POTENT VANILLOID RECEPTOR AGONISTS AND ANALGESICS, COMPOSITIONS AND USES THEREOF | PACIFIC CORP (KR) | 2005-12-14 | — | — | EP | disclosed |
| US-6476076-B1 | Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof | PACIFIC CORPORATION (KR) | 2002-11-05 | — | — | US | disclosed |