Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376950 | 0.90 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL6380445 | 0.88 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL6380875 | 0.88 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL6376903 | 0.88 | KDM4E (0.39) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL6602742 | 0.86 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6381613 | 0.85 | GRIN2D (0.42) | GRIA1GRIA2GRIA3GRIA4EGLN1 | |
| SCHEMBL6375169 | 0.79 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6601414 | 0.79 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6374571 | 0.79 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6605387 | 0.79 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | claimed |
| EP-1156047-B1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1156047-A1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |