Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918204 | 1.00 | NPC1 (0.66) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| Hydrochloric Acid SCHEMBL10982713 | 0.98 | NPC1 (0.64) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| SCHEMBL16695399 | 0.89 | AKR1C3 (0.71) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| SCHEMBL31154456 | 0.89 | AKR1C3 (0.71) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| Bicarbonate SCHEMBL1719769 | 0.88 | IDO1 (0.51) | NPC1RAB9AFFAR2MAPTDEGS1 | |
| SCHEMBL10896665 | 0.85 | MAPT (0.51) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| SCHEMBL9938128 | 0.85 | MAPT (0.51) | NPC1RAB9AAKR1C3AKR1C1FFAR2 | |
| Acetic Acid SCHEMBL28980245 | 0.84 | IDO1 (0.49) | NPC1RAB9AFFAR2MAPTDEGS1 | |
| Carbamic Acid SCHEMBL1569088 | 0.84 | IDO1 (0.49) | NPC1RAB9AFFAR2MAPTDEGS1 | |
| SCHEMBL3219203 | 0.83 | MAPT (0.50) | NPC1RAB9AFFAR2MAPTDEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036772-A | Synthesis method of beta-pinacol borate-alkyl ketone compound | 陇东学院 | 2026-05-15 | — | — | CN | claimed |
| CN-115275216-B | Pore-forming composition and application thereof | 东风汽车集团股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-115490582-A | Preparation method of fluorine-containing biphenyl alkene negative monomer liquid crystal compound | 烟台德润液晶材料有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-115275216-A | Pore-forming composition and application thereof | 东风汽车集团股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-212189064-U | 4- (4-chlorophenyl) cyclohexanecarboxylic acid production system | 日照巴洛特药业有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-104628555-B | A kind of synthetic method of pharmaceutical intermediate 4-(4-chlorphenyl) cyclohexyl-1-formic acid | 烟台蓓丰医药科技有限公司 | 2016-11-30 | — | — | CN | claimed |
| CN-105622381-A | Atovaquone synthesis technology | QINGDAO SHOUTAI AGRICULTURAL SCIENCE & TECH CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-104628555-A | Synthesis method of drug intermediate 4-(4-chlorphenyl) cyclohexyl-1-formic acid | YANTAI BIOFENGS PHARM TECH CO LTD | 2015-05-20 | — | — | CN | claimed |
| US-8598387-B2 | Process for the preparation of atovaquone | GLAXO GROUP LIMITED (GB) | 2013-12-03 | — | — | US | claimed |
| EP-2651868-A2 | PROCESS FOR THE PREPARATION OF ATOVAQUONE | Glaxo Group Limited (GB) | 2013-10-23 | — | — | EP | claimed |
| US-20110004024-A1 | PREPARATION OF NAPHTHOQUINONE COMPOUNDS USING 2,3-DIHALONAPHTHOQUINONE | ALKEM LABORATORIES LIMITED (IN) | 2011-01-06 | — | — | US | claimed |
| EP-2250145-A2 | PREPARATION OF NAPHTHOQUINONE COMPOUNDS USING 2, 3-DIHALONAPTHOQUINONE | Alkem Laboratories Ltd. (IN) | 2010-11-17 | — | — | EP | claimed |
| CN-101774901-A | Method for preparing atovaquone | WUHAN TITON BIOTECH LTD | 2010-07-14 | — | — | CN | claimed |
| CN-101265171-B | Technique for synthesizing atovaquone | CHONGQING HALLOCHEM PHARMA CO LTD | 2010-06-02 | — | — | CN | claimed |
| WO-2010023686-A2 | CRYSTALLINE FORM OF 2-CHLORO-3-[4-(4-CHLOROPHENYL) CYCLOHEXYL] [1,4]NAPHTHOQUINONE, PROCESS FOR THE SAME AND USE FOR PRODUCING 2-[4-(4-CHLOROPHENYL)CYCLOHEXYL]-3- HYDROXY- 1,4- NAPHTHOQUINONE | MATRIX LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | WO | claimed |
| WO-2010001379-A1 | A PROCESS FOR PREPARING ATOVAQUONE AND ASSOCIATE INTERMEDIATES | CHEMAGIS LTD. (IL) | 2010-01-07 | — | — | WO | claimed |
| WO-2009122432-A2 | PREPARATION OF NAPHTHOQUINONE COMPOUNDS USING 2, 3-DIHALONAPTHOQUINONE | ALKEM LABORATORIES LTD. (IN) | 2009-10-08 | — | — | WO | claimed |
| WO-2009007991-A2 | A NEW PROCESS FOR PREPARATION OF ATOVAQUONE AND NOVEL INTERMEDIATES THEREOF | IPCA LABORATORIES LIMITED (IN) | 2009-01-15 | — | — | WO | claimed |
| WO-2008122988-A1 | PROCESS FOR PREPARATION OF ATOVAQUONE AND THE CONVERSION OF CIS-ISOMER TO TRANS- ISOMER | CADILA HEALTHCARE LIMITED (IN) | 2008-10-16 | — | — | WO | claimed |
| CN-101265171-A | Technique for synthesizing atovaquone | CHONGQING HALLOCHEM PHARMA CO (CN) | 2008-09-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004024-A1 | PREPARATION OF NAPHTHOQUINONE COMPOUNDS USING 2,3-DIHALONAPHTHOQUINONE | RECQL, NQO2, NQO1 | NPC1 1929/4885RAB9A 2874/4885AKR1C3 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.