Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141649 | 0.84 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4HTR2B | |
| SCHEMBL5952830 | 0.83 | PDCD1 (0.34) | PDCD1CD274ALDH1A1HPGDBCL2L1 | |
| SCHEMBL2561824 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL27423782 | 0.82 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7724565 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL271771 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6436500 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6433747 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4HTR2B | |
| Fluoride SCHEMBL7638687 | 0.81 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL60641 | 0.80 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | PDCD1 2265/4885CD274 2659/4885ALDH1A1 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.