SCHEMBL6375829

SCHEMBL6375829

CCON=C(N[C@H]1CCC(C(=O)N(C)C)C[C@H]1NC(=O)c1nc2c(s1)CN(C)CC2)C(=O)Nc1ccc(Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.66
F2 P00734 2/20 0.66
F5 P12259 1/20 0.66
PLAT P00750 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2187893 1.00 F10 (0.66) F10F2F5PLAT
SCHEMBL2187897 1.00 F10 (0.66) F10F2F5PLAT
SCHEMBL1322311 0.93 F10 (0.67) F10F2F5PLAT
SCHEMBL14262211 0.93 F10 (0.67) F10F2F5PLAT
SCHEMBL12101171 0.93 F10 (0.67) F10F2F5PLAT
SCHEMBL1322309 0.93 F10 (0.67) F10F2F5PLAT
Hydrochloric Acid SCHEMBL3304848 0.93 F10 (0.67) F10F2F5PLAT
Hydrochloric Acid SCHEMBL3304851 0.93 F10 (0.67) F10F2F5PLAT
SCHEMBL2188664 0.93 F10 (0.62) F10F2F5PLAT
SCHEMBL2188661 0.93 F10 (0.62) F10F2F5PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed