Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 11/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 11/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 11/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 11/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 7/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377983 | 0.93 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6376486 | 0.85 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6374580 | 0.85 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6382562 | 0.84 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6377650 | 0.84 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6381619 | 0.84 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6376910 | 0.83 | GRIA1 (0.62) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6375949 | 0.83 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6602498 | 0.82 | GRIA1 (0.71) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6607049 | 0.82 | GRIA1 (0.81) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156047-B1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1156047-A1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |