Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.76 |
| ▸ | PPARG | P37231 | 10/20 | 0.76 |
| ▸ | PPARD | Q03181 | 6/20 | 0.76 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.59 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.59 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.59 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.59 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.59 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374875 | 1.00 | PPARA (0.76) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6377253 | 0.94 | PPARA (0.85) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6377198 | 0.94 | PPARA (0.85) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6373738 | 0.92 | PPARA (0.89) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6375902 | 0.92 | PPARA (0.89) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6376945 | 0.91 | PPARA (0.86) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6375543 | 0.91 | PPARA (0.86) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6377702 | 0.89 | PPARA (0.76) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6375343 | 0.89 | PPARA (0.76) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6373752 | 0.86 | PPARA (1.00) | PPARAPPARGPPARDPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184366-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN SEIYAKU KK (JP) | 2005-02-09 | — | — | EP | claimed |
| US-6506797-B1 | Activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha alpha ), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-01-14 | — | — | US | claimed |
| EP-1184366-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-03-06 | — | — | EP | claimed |