Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944741 | 1.00 | GRIA4 (0.65) | GRIA4POLBLSSALDH1A1MEN1 | |
| SCHEMBL5991959 | 0.85 | GRIA4 (0.63) | GRIA4POLBLSSALDH1A1MEN1 | |
| SCHEMBL12076289 | 0.82 | GRIA4 (0.70) | GRIA4POLBALDH1A1MEN1KMT2A | |
| SCHEMBL8199627 | 0.80 | GRIA4 (0.70) | GRIA4POLBALDH1A1MEN1KMT2A | |
| Mibampator SCHEMBL6660037 | 0.79 | GRIA4 (1.00) | GRIA4POLB | |
| Mibampator SCHEMBL3045499 | 0.79 | GRIA4 (1.00) | GRIA4POLB | |
| Mibampator SCHEMBL3074747 | 0.79 | GRIA4 (1.00) | GRIA4POLB | |
| SCHEMBL10312250 | 0.79 | POLB (0.64) | GRIA4POLBALDH1A1MEN1KMT2A | |
| SCHEMBL15663101 | 0.77 | GRIA4 (0.62) | GRIA4POLBALDH1A1MEN1KMT2A | |
| SCHEMBL6784069 | 0.76 | GRIA4 (0.68) | GRIA4MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294683-B1 | A PROCESS FOR PREPARING BIPHENYL COMPOUNDS | LILLY CO ELI (US) | 2005-11-30 | — | — | EP | disclosed |