Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24040550 | 1.00 | HCAR2 (0.65) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL19029663 | 1.00 | HCAR2 (0.65) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL19029632 | 1.00 | HCAR2 (0.65) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL27407116 | 1.00 | HCAR2 (0.65) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL1246093 | 1.00 | HCAR2 (0.65) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL11045900 | 0.93 | HCAR2 (0.74) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL1246524 | 0.93 | HCAR2 (0.74) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL10780616 | 0.93 | HCAR2 (0.74) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL8648496 | 0.92 | HCAR2 (0.57) | HCAR2TSHRTP53ALDH1A1HIF1A | |
| SCHEMBL17187308 | 0.92 | HCAR2 (0.57) | HCAR2TSHRTP53ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | claimed |
| EP-2644578-A1 | Copolymer for dispersant for cement, dispersant for cement, and cement composition | Technische Universität München (DE) | 2013-10-02 | — | — | EP | disclosed |
| EP-1345985-B9 | COUPLING OF REINFORCING FIBRES TO RESINS IN CURABLE COMPOSITES | LICOTEC PTY LTD (AU) | 2012-02-22 | — | — | EP | disclosed |
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | disclosed |
| EP-1345985-B1 | COUPLING OF REINFORCING FIBRES TO RESINS IN CURABLE COMPOSITES | LICOTEC PTY LTD (AU) | 2011-05-18 | — | — | EP | disclosed |