Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 7/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380176 | 1.00 | CSNK2A1 (0.54) | CSNK2A1EGFRESRRAFTOMEN1 | |
| SCHEMBL6374698 | 0.88 | HPGD (0.56) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6374694 | 0.88 | HPGD (0.56) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6375854 | 0.86 | ESRRA (0.51) | CSNK2A1EGFRESRRAMEN1KMT2A | |
| SCHEMBL6375857 | 0.86 | ESRRA (0.51) | CSNK2A1EGFRESRRAMEN1KMT2A | |
| SCHEMBL6373841 | 0.83 | CSNK2A1 (0.78) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6373838 | 0.83 | CSNK2A1 (0.78) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6381013 | 0.83 | CSNK2A1 (0.50) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6381011 | 0.83 | CSNK2A1 (0.50) | CSNK2A1ESRRAFTOMEN1KMT2A | |
| SCHEMBL6374579 | 0.83 | CSNK2A1 (0.48) | CSNK2A1ESRRAFTOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | claimed |
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |