Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386676 | 0.89 | SRC (0.57) | SRCFYNMAP2K1RAF1MAPK3 | |
| SCHEMBL6380183 | 0.85 | SRC (0.81) | SRCFYNMAP2K1ABL1BCR | |
| SCHEMBL6383464 | 0.85 | SRC (0.64) | SRCFYNABL1BCR | |
| SCHEMBL6382264 | 0.84 | EGFR (0.57) | SRCFYNMAP2K1ABL1BCR | |
| SCHEMBL6380678 | 0.84 | SRC (0.54) | SRCFYNMAP2K1ABL1BCR | |
| SCHEMBL6382212 | 0.84 | SRC (0.55) | SRCMAP2K1RAF1MAPK3MAPK1 | |
| SCHEMBL6382844 | 0.82 | SRC (0.53) | SRCMAP2K1ABL1BCR | |
| SCHEMBL6382853 | 0.82 | EGFR (0.58) | SRCMAP2K1RAF1MAPK3MAPK1 | |
| SCHEMBL6385112 | 0.81 | MAP2K1 (0.57) | SRCMAP2K1RAF1MAPK3MAPK1 | |
| SCHEMBL6382267 | 0.81 | SRC (0.58) | SRCFYNABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |