Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.68 |
| ▸ | MMP13 | P45452 | 9/20 | 0.40 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381782 | 0.96 | FDFT1 (0.74) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6382904 | 0.86 | FDFT1 (0.53) | FDFT1MMP13MMP2 | |
| SCHEMBL5225732 | 0.85 | FDFT1 (0.63) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6379076 | 0.85 | FDFT1 (0.51) | FDFT1MMP13MMP2 | |
| SCHEMBL6377358 | 0.85 | FDFT1 (0.51) | FDFT1MMP13MMP2 | |
| SCHEMBL6377333 | 0.84 | FDFT1 (0.92) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6377329 | 0.84 | FDFT1 (0.92) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6375468 | 0.84 | FDFT1 (0.92) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL5224937 | 0.82 | FDFT1 (0.71) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL5224246 | 0.82 | FDFT1 (0.71) | FDFT1MMP13MMP2CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |