Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205304 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2CPB1TSHRKDM4E | |
| SCHEMBL205160 | 0.87 | GRIK1 (0.56) | GRIK1GRIK2CPB1TSHRKDM4E | |
| SCHEMBL17706793 | 0.85 | EP300 (0.57) | GRIK1CPB1TSHRKDM4EEP300 | |
| Lithium SCHEMBL31004870 | 0.85 | GRIK1 (0.54) | GRIK1GRIK2CPB1TSHRKDM4E | |
| SCHEMBL17706756 | 0.85 | EP300 (0.57) | GRIK1CPB1TSHRKDM4EEP300 | |
| SCHEMBL206840 | 0.85 | EP300 (0.57) | GRIK1CPB1TSHRKDM4EEP300 | |
| SCHEMBL31004918 | 0.85 | GRIK1 (0.54) | GRIK1GRIK2CPB1TSHRKDM4E | |
| SCHEMBL271144 | 0.84 | EP300 (0.60) | GRIK1CPB1EP300CYP2C19RECQL | |
| SCHEMBL205684 | 0.84 | EP300 (0.60) | GRIK1CPB1EP300CYP2C19RECQL | |
| SCHEMBL17706807 | 0.84 | EP300 (0.60) | GRIK1CPB1EP300CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275394-A1 | MODIFIED POLYVINYL ALCOHOL AND WATER-SOLUBLE FILM | KURARAY CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-1527039-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | Basell Poliolefine Italia S.P.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| EP-1527040-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | Basel Poliolefine Italia SpA (IT) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004014838-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014839-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | BASEL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-19 | — | — | WO | disclosed |