Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382006 | 0.94 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL8150053 | 0.87 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL6382071 | 0.87 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL6385833 | 0.85 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL8150230 | 0.85 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL6383772 | 0.85 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL1418005 | 0.84 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL1418008 | 0.84 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL6383578 | 0.83 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL6383583 | 0.83 | EGFR (0.85) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |