Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059529 | 0.79 | NPC1 (0.40) | PTGER4NPC1MAPT | |
| SCHEMBL2749549 | 0.76 | HSD17B10 (0.52) | PTGER4NPC1 | |
| SCHEMBL2750918 | 0.74 | NPC1 (0.44) | PTGER4NPC1MAPT | |
| SCHEMBL31638946 | 0.73 | NPC1 (0.42) | NPC1MAPT | |
| Dimethylamine SCHEMBL6021489 | 0.73 | NPC1 (0.37) | NPC1MAPT | |
| SCHEMBL31085038 | 0.71 | KDM4E (0.50) | NPC1MAPT | |
| SCHEMBL30938916 | 0.71 | ESR2 (0.36) | PTGER4NPC1MAPT | |
| SCHEMBL30938860 | 0.70 | PTGER4 (0.36) | PTGER4NPC1MAPT | |
| SCHEMBL19023458 | 0.70 | BRD4 (0.44) | NPC1MAPT | |
| SCHEMBL20028655 | 0.70 | NPC1 (0.40) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119648-B2 | Arthritis, obesity, (non-insulin dependent) diabetes calcitonin-induced osteoporosis; administering allograft transplantation; dipeptidyl peptidase-IV (DPP-IV) inhibitors | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2012-02-21 | — | — | US | disclosed |