Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 16/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381927 | 0.85 | EGFR (0.51) | EGFRERBB2GAK | |
| SCHEMBL1893072 | 0.85 | EGFR (0.55) | EGFRERBB2GAK | |
| SCHEMBL6383209 | 0.84 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL6383946 | 0.81 | EGFR (0.61) | EGFRERBB2GAK | |
| SCHEMBL6379739 | 0.81 | EGFR (0.62) | EGFRERBB2GAK | |
| SCHEMBL4961565 | 0.80 | EGFR (0.58) | EGFRERBB2GAK | |
| SCHEMBL1892093 | 0.77 | EGFR (0.51) | EGFRERBB2GAK | |
| SCHEMBL6383202 | 0.77 | EGFR (0.60) | EGFRERBB2 | |
| SCHEMBL4962089 | 0.76 | MAP3K8 (0.57) | EGFRERBB2GAK | |
| SCHEMBL1896747 | 0.75 | EGFR (0.68) | EGFRERBB2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |