Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384942 | 0.90 | HDAC4 (0.34) | HDAC4HDAC2HDAC8GSTP1AKR1C3 | |
| SCHEMBL6385698 | 0.88 | HDAC4 (0.33) | HDAC4HDAC2HDAC8GSTP1AKR1C3 | |
| SCHEMBL6384551 | 0.86 | HDAC4 (0.32) | HDAC4HDAC2HDAC8GSTP1 | |
| SCHEMBL5951803 | 0.84 | HDAC4 (0.35) | HDAC4HDAC2HDAC8GSTP1ERN1 | |
| SCHEMBL6384375 | 0.83 | — | — | |
| SCHEMBL3401448 | 0.83 | HDAC4 (0.31) | HDAC4HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL3401450 | 0.82 | HDAC4 (0.30) | HDAC4HDAC2HDAC8 | |
| SCHEMBL3403447 | 0.82 | HDAC4 (0.30) | HDAC4HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL3403449 | 0.81 | HDAC4 (0.31) | HDAC4HDAC2HDAC8 | |
| SCHEMBL6386670 | 0.80 | CA12 (0.32) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567560-A1 | ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004052945-A1 | ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-24 | — | — | WO | disclosed |