SCHEMBL638667

SCHEMBL638667

F[B-](F)(F)F.N#[N+]c1ccc(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.41
TSHR P16473 5/20 0.37
CYP3A4 P08684 4/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPK1 P28482 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 3/20 0.34
GABRA1 P14867 3/20 0.34
GABRG2 P18507 3/20 0.34
GABRB3 P28472 3/20 0.34
GABRB1 P18505 2/20 0.34
GABRB2 P47870 2/20 0.34
ALDH1A1 P00352 3/20 0.33
IDO1 P14902 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929218 1.00 TP53 (0.41) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL27701066 0.98 TP53 (0.39) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL633223 0.91 TP53 (0.48) TP53TSHRCYP3A4HSD17B10MAPK1
Hydrochloric Acid SCHEMBL3814343 0.89 TP53 (0.46) TP53TSHRCYP3A4HSD17B10MAPK1
Hydrochloric Acid SCHEMBL28462430 0.89 TP53 (0.46) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL636363 0.85 TP53 (0.42) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL11585263 0.85 TP53 (0.42) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL10935092 0.84 TP53 (0.38) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL9745484 0.83 TP53 (0.41) TP53TSHRCYP3A4HSD17B10MAPK1
SCHEMBL30739512 0.83 TP53 (0.41) TP53TSHRCYP3A4HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60143768-A None JP disclosed
CN-117792148-A Method for modifying two-dimensional material nano holes at fixed point 北京大学 2024-03-29 CN disclosed
CN-116751174-A Synthesis method of aryl substituted 1,3, 4-oxadiazole derivative 铜陵欣诺科新材料有限公司 2023-09-15 CN disclosed
CN-112789016-B Feces indicator for absorbent article, feces indicator material, application thereof, and absorbent article 尤妮佳股份有限公司 2022-09-20 CN disclosed
CN-112789016-A Feces indicator for absorbent article, feces indicator material, application thereof, and absorbent article 尤妮佳股份有限公司 2021-05-11 CN disclosed
EP-2080554-B1 Method of storing analytical reagent into microfluidic device SAMSUNG ELECTRONICS CO LTD (KR) 2013-03-20 EP disclosed
EP-2015876-B1 COATING COMPOSITIONS SUITABLE FOR USE AS A WOOD STAIN AND/OR TONER PPG IND OHIO INC (US) 2012-02-22 EP disclosed
US-7691484-B2 Coating compositions suitable for use as a wood stain and/or toner PPG INDUSTRIES OHIO, INC. (US) 2010-04-06 US disclosed
US-7579073-B2 Coating compositions suitable for use as a wood stain and/or toner PPG INDUSTRIES OHIO, INC. (US) 2009-08-25 US disclosed
EP-2080554-A1 Method of storing analytical reagent into microfluidic device Samsung Electronics Co.,Ltd. (KR) 2009-07-22 EP disclosed
US-4345911-A DIAZONIUM SALT OF PYRAZOLE BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1982-08-24 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
US-4309482-A MAGNETIC TAPE HAVING POLYEPOXIDE PROTECTIVE COATING MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-01-05 US disclosed
US-4289595-A PHOTOINITIATOR WHICH DECOMPOSES TO LEWIS ACID POLYMERIZATION CATALYST AMERICAN CAN COMPANY (US) 1981-09-15 US disclosed
EP-0025889-A1 Diagnostic agent for the detection of bilirubin in body fluids and use of a reagent suitable therefor BEHRINGWERKE Aktiengesellschaft (DE) 1981-04-01 EP disclosed
US-4250006-A USING ONIUM PHOTOINITIATORS AND RADIATION TO EFFECT CURING; TACK-FREE; CANS AMERICAN CAN COMPANY (US) 1981-02-10 US disclosed
US-4246298-A THE EPOXY PREPOLYMER CONTAINING A CATALYST PRECURSOR AMERICAN CAN COMPANY (US) 1981-01-20 US disclosed
EP-0022240-A1 Reagent for bilirubin determination BEHRINGWERKE Aktiengesellschaft (DE) 1981-01-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed