Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL4958369 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4957183 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL216857 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL30457906 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1919965 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28613824 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL14335789 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL10952183 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22556628 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL15667258 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113184966-B | Method for preparing carbon quantum loaded polysilicate aluminum ferric flocculant by using bauxite and tuff | 常熟理工学院 | 2022-05-24 | — | — | CN | claimed |
| CN-113184966-B | Method for preparing carbon quantum loaded polysilicate aluminum ferric flocculant by using bauxite and tuff | 常熟理工学院 | 2022-05-24 | — | — | CN | disclosed |
| CN-113184966-A | Method for preparing carbon quantum loaded polysilicate aluminum ferric flocculant by using bauxite and tuff | 常熟理工学院 | 2021-07-30 | — | — | CN | disclosed |
| US-8707978-B2 | Breaking pumpable hydrocarbon gels | CST PERFORMANCE PRODUCTS CORP. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130081819-A1 | Breaking pumpable hydrocarbon gels | Conlen Surfactant Technology, Inc. | 2013-04-04 | — | — | US | disclosed |
| US-20130025857-A1 | Preserving oil gravity | Conlen Surfactant Technology, Inc. | 2013-01-31 | — | — | US | disclosed |
| US-20050100593-A1 | Capsule film composition and gelatin capsule | AJINOMOTO CO., INC. | 2005-05-12 | — | — | US | disclosed |