Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4842967 | 0.99 | CACNA1B (0.57) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL5117571 | 0.93 | CACNA1B (0.57) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4842738 | 0.92 | CACNA1B (0.56) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL5110983 | 0.92 | CACNA1B (0.69) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL7768817 | 0.92 | CACNA1B (0.57) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4844941 | 0.92 | CACNA1B (0.55) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL3910290 | 0.91 | CACNA1B (0.53) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4845373 | 0.91 | CACNA1B (0.56) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL7039298 | 0.91 | CACNA1B (0.57) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL5124105 | 0.90 | CACNA1B (0.55) | CACNA1BCYP2C19SMN1; SMN2L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903119-B1 | Amino acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-07 | — | — | US | claimed |
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | claimed |
| US-7427634-B2 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427634-B2 | Amino acid derivatives and pharmaceutical composition comprising, as active ingredients, them | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-23 | — | — | US | disclosed |
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |