⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874286 | 0.82 | — | — | |
| SCHEMBL231704 | 0.79 | — | — | |
| SCHEMBL7505 | 0.78 | — | — | |
| SCHEMBL974303 | 0.77 | — | — | |
| SCHEMBL8095601 | 0.76 | — | — | |
| SCHEMBL3829351 | 0.76 | — | — | |
| SCHEMBL4664231 | 0.76 | — | — | |
| SCHEMBL20755 | 0.76 | — | — | |
| SCHEMBL919371 | 0.76 | — | — | |
| SCHEMBL5159201 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1769079-B1 | ENZYMATIC PRODUCTION OF (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2017-06-28 | — | — | EP | claimed |
| US-20060009589-A1 | Enzymatic preparation of (meth)acrylic esters | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-12 | — | — | US | claimed |
| US-5663397-A | MULTISTAGE PROCESS FORMING OXYSILICON RING ENLARGEMENT BY REACTION WITH ACID HALIDE IN THE PRESENCE OF PALLADIUM CATALYST AND ORGANIC BASE | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1997-09-02 | — | — | US | claimed |
| US-20170037016-A1 | GUANIDINE COMPOUNDS AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2017-02-09 | — | — | US | disclosed |
| US-9475782-B2 | Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-10-25 | — | — | US | disclosed |
| US-9296697-B2 | Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-HT5-receptors | ABBOTT LABORATORIES (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150218146-A1 | SUBSTITUTED OXINDOLE DERIVATIVES, MEDICAMENTS CONTAINING SAID DERIVATIVES AND USE THEREOF | ABBVIE DEUTSCHLAND (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150183770-A1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2015-07-02 | — | — | US | disclosed |
| US-9006276-B2 | Substituted oxindole derivatives, medicaments containing said derivatives and use thereof | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-04-14 | — | — | US | disclosed |
| US-8921406-B2 | 5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20140221371-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-08-07 | — | — | US | disclosed |
| EP-0093084-B1 | 1-CARBOXYALKANOYLINDOLINE-2-CARBOXYLIC-ACID ESTERS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTIC USE | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |
| US-4479963-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
| EP-0093084-A1 | 1-Carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |
| US-4401818-A | HYPOTENSIVE AGENTS, CARDIOACTIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-08-30 | — | — | US | disclosed |
| US-4374847-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |
| US-3996193-A | POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER | THE DOW CHEMICAL COMPANY (US) | 1976-12-07 | — | — | US | disclosed |