Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127043 | 0.80 | SMN1; SMN2 (0.37) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27625813 | 0.80 | SMN1; SMN2 (0.38) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6395180 | 0.79 | — | — | |
| SCHEMBL25045811 | 0.76 | CA1 (0.39) | CA1CA2ALOX15 | |
| SCHEMBL1259256 | 0.76 | CA1 (0.34) | CA1CA2ALOX15 | |
| SCHEMBL4598217 | 0.74 | CA1 (0.33) | CA1CA2ALOX15ALDH1A1 | |
| SCHEMBL23230292 | 0.74 | CA1 (0.33) | CA1CA2ALOX15ALDH1A1 | |
| SCHEMBL28758522 | 0.74 | TSHR (0.34) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4394723 | 0.73 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL11138013 | 0.72 | CA1 (0.45) | TSHRCA1CA2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |