⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524048 | 0.74 | — | — | |
| SCHEMBL18032665 | 0.54 | — | — | |
| SCHEMBL4362773 | 0.43 | — | — | |
| SCHEMBL186926 | 0.43 | — | — | |
| SCHEMBL329489 | 0.39 | — | — | |
| SCHEMBL9787221 | 0.33 | — | — | |
| SCHEMBL10545264 | 0.33 | — | — | |
| SCHEMBL380648 | 0.33 | — | — | |
| SCHEMBL21951311 | 0.27 | — | — | |
| SCHEMBL31203085 | 0.27 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227345-A1 | Quorum sensing signaling in bacteria | AURORA BIOSCIENCES CORPORATION (US) | 2005-10-13 | — | — | US | disclosed |
| US-6855513-B1 | Quorum sensing signaling in bacteria | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004083385-A2 | QUORUM SENSING SIGNALING IN BACTERIA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20040033549-A1 | Identifying modulator of biofilm formation and/or infection for treatment and prevention of infections, skin, periodontal and respiratory system disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| EP-1250450-A2 | QUORUM SENSING SIGNALING IN BACTERIA | University of Iowa Research Foundation Inc. (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001018248-A2 | QUORUM SENSING SIGNALING IN BACTERIA | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-03-15 | — | — | WO | disclosed |