Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972217 | 0.83 | TSHR (0.44) | TSHR | |
| SCHEMBL27819968 | 0.78 | GAA (0.40) | TSHR | |
| SCHEMBL27863810 | 0.76 | GAA (0.39) | TSHR | |
| SCHEMBL25773441 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL30480105 | 0.75 | TSHR (0.66) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25769637 | 0.74 | TSHR (0.40) | TSHR | |
| SCHEMBL6971061 | 0.73 | — | — | |
| SCHEMBL6971056 | 0.73 | — | — | |
| SCHEMBL27601993 | 0.72 | MCL1 (0.39) | TSHRMCL1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21337781 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |