Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.65 |
| ▸ | INSR | P06213 | 4/20 | 0.65 |
| ▸ | TEK | Q02763 | 4/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.65 |
| ▸ | CSF1R | P07333 | 2/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729223 | 0.93 | KDR (0.57) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6398204 | 0.92 | KDR (0.56) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6404350 | 0.91 | KDR (0.54) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6401464 | 0.89 | KDR (0.54) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6394106 | 0.89 | KDR (0.52) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6397238 | 0.89 | KDR (0.51) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6395289 | 0.87 | CFTR (0.54) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6315370 | 0.87 | KDR (0.50) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6401560 | 0.87 | CFTR (0.55) | KDRINSRTEKPDGFRBPDGFRA | |
| SCHEMBL6393385 | 0.86 | KDR (0.66) | KDRINSRTEKPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549645-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | Johnson & Johnson Pharmaceutical Research & Development, Inc. (US) | 2005-07-06 | — | — | EP | claimed |
| US-20040110758-A1 | 4,6-Diaminosubstituted-2-[oxy or aminoxy]-[1,3,5]triazines as protein tyrosine kinase inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-06-10 | — | — | US | claimed |
| WO-2004031184-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. (US) | 2004-04-15 | — | — | WO | claimed |
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FOUNTAIN THERAPEUTICS INC (US) | 2024-05-16 | — | — | US | disclosed |
| CN-106232595-B | Diaminotriazine compounds as herbicides | 巴斯夫欧洲公司 | 2020-01-14 | — | — | CN | disclosed |
| US-9822105-B2 | Diaminotriazine compounds as herbicides | BASF SE (DE) | 2017-11-21 | — | — | US | disclosed |
| EP-3134400-A1 | DIAMINOTRIAZINE COMPOUNDS AS HERBICIDES | BASF SE (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20170050954-A1 | Diaminotriazine Compounds as Herbicides | BASF SE (DE) | 2017-02-23 | — | — | US | disclosed |
| CN-106232595-A | Diaminourea triaizine compounds as herbicide | 巴斯夫欧洲公司 | 2016-12-14 | — | — | CN | disclosed |
| WO-2015162169-A1 | DIAMINOTRIAZINE COMPOUNDS AS HERBICIDES | BASF SE (DE) | 2015-10-29 | — | — | WO | disclosed |
| EP-1549645-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | Johnson & Johnson Pharmaceutical Research & Development, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040110758-A1 | 4,6-Diaminosubstituted-2-[oxy or aminoxy]-[1,3,5]triazines as protein tyrosine kinase inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-06-10 | — | — | US | disclosed |
| WO-2004031184-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. (US) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FGFR1, FRS2, FGFR2 | KDR 5/4885INSR 309/4885TEK 6/4885 |
| US-20040110758-A1 | 4,6-Diaminosubstituted-2-[oxy or aminoxy]-[1,3,5]triazines as protein tyrosine kinase inhibitors | TIE1, KDR, FLT1 | KDR 2/4885INSR 358/4885TEK 5/4885 |
| US-20170050954-A1 | Diaminotriazine Compounds as Herbicides | NR4A3, RXRB, CBR3 | KDR 936/4885INSR 835/4885TEK 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.