Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396779 | 0.97 | IDO1 (0.45) | IDO1MEN1KMT2AESR1ESR2 | |
| SCHEMBL9060534 | 0.81 | KDM1A (0.53) | IDO1MEN1KMT2A | |
| SCHEMBL9060529 | 0.81 | KDM1A (0.53) | IDO1MEN1KMT2A | |
| SCHEMBL3863496 | 0.81 | KDM1A (0.53) | IDO1MEN1KMT2A | |
| SCHEMBL9060540 | 0.81 | KDM1A (0.53) | IDO1MEN1KMT2A | |
| SCHEMBL9391060 | 0.78 | KMT2A (0.65) | MEN1KMT2AHPGDALOX15CDK4 | |
| SCHEMBL9386543 | 0.78 | KMT2A (0.65) | MEN1KMT2AHPGDALOX15CDK4 | |
| SCHEMBL9387582 | 0.78 | KMT2A (0.65) | MEN1KMT2AHPGDALOX15CDK4 | |
| SCHEMBL11007946 | 0.78 | IDO1 (0.52) | IDO1MEN1KMT2AESR1ESR2 | |
| SCHEMBL9387499 | 0.78 | KMT2A (0.65) | MEN1KMT2AHPGDALOX15CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2005-03-03 | — | — | US | claimed |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-01-15 | — | — | US | claimed |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2002-08-15 | — | — | US | claimed |
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2005-03-03 | — | — | US | disclosed |
| US-6838583-B2 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and the methods of using the same | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1409443-A2 | NON-HALOGENATED NAPHTHOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | WARNER-LAMBERT COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-01-15 | — | — | US | disclosed |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2002-08-15 | — | — | US | disclosed |
| WO-2002050001-A2 | NON-HALOGENATED NAPHTHOL COMPOUNDS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | WARNER-LAMBERT COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | IDO1 2002/4885MEN1 2321/4885KMT2A 4054/4885 |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | IDO1 2002/4885MEN1 2321/4885KMT2A 4054/4885 |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | IDO1 2002/4885MEN1 2321/4885KMT2A 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.