Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | ESRRG | P62508 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 4/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.52 |
| ▸ | BCR | P11274 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174944 | 0.91 | ESR1 (0.73) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL16581467 | 0.86 | ESR1 (0.64) | ESR1ESR2CYP3A4HPGDTSHR | |
| Bisphenol A SCHEMBL5141906 | 0.83 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL9785062 | 0.83 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL3149692 | 0.83 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL6277528 | 0.83 | ESR1 (0.84) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL5604262 | 0.82 | ESR1 (0.64) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL27235663 | 0.82 | RXRB (0.60) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL11223777 | 0.81 | ESR1 (0.68) | ESR1ESR2CYP3A4HPGDTSHR | |
| SCHEMBL24617945 | 0.80 | ESR1 (1.00) | ESR1ESR2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050247913-A1 | Phosphorous ester compound, process for producing the same, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-11-10 | — | — | US | disclosed |