Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 9/20 | 0.83 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400565 | 0.91 | P2RY2 (1.00) | P2RY2P2RY4P2RY6 | |
| SCHEMBL6393348 | 0.86 | P2RY2 (0.82) | P2RY2P2RY4NPC1RAB9AKDM4E | |
| SCHEMBL6394303 | 0.84 | P2RY2 (0.82) | P2RY2P2RY4DNPH1P2RY6 | |
| SCHEMBL6394999 | 0.84 | P2RY2 (0.65) | P2RY2P2RY4NPC1RAB9ACYP1A2 | |
| Phosphoric Acid SCHEMBL6400578 | 0.82 | P2RY2 (0.63) | P2RY2SCDNPC1RAB9AMEN1 | |
| SCHEMBL6886614 | 0.81 | P2RY2 (0.83) | P2RY2P2RY4P2RY6 | |
| Benzoic Acid SCHEMBL6397602 | 0.79 | P2RY2 (0.60) | P2RY2P2RY4SCDNPC1RAB9A | |
| SCHEMBL6400291 | 0.79 | P2RY2 (0.82) | P2RY2P2RY4P2RY6ALDH1A1GAA | |
| SCHEMBL6395433 | 0.77 | P2RY2 (0.84) | P2RY2P2RY4P2RY6DYRK1A | |
| SCHEMBL6393343 | 0.77 | P2RY2 (1.00) | P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | CELLTECH R & D LIMITED (GB) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | P2RY1, P2RY11, P2RY13 | P2RY2 4/4885P2RY4 6/4885DNPH1 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.