⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604622 | 0.97 | — | — | |
| SCHEMBL30604628 | 0.97 | — | — | |
| SCHEMBL14344789 | 0.76 | — | — | |
| SCHEMBL26363058 | 0.74 | — | — | |
| SCHEMBL4104657 | 0.73 | — | — | |
| SCHEMBL25696319 | 0.73 | — | — | |
| SCHEMBL25117899 | 0.72 | — | — | |
| SCHEMBL18756423 | 0.69 | — | — | |
| SCHEMBL23213395 | 0.69 | — | — | |
| SCHEMBL14999508 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| US-10723698-B2 | Inhibitors of PRMT5 and methods of their use | THE OHIO STATE UNIVERSITY (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190270707-A1 | INHIBITORS OF PRMT5 AND METHODS OF THEIR USE | THE OHIO STATE UNIVERSITY | 2019-09-05 | — | — | US | disclosed |
| US-6891005-B2 | Bridged metal complexes for gas phase polymerizations | BP CHEMICALS LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |