Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.76 |
| ▸ | F3 | P13726 | 14/20 | 0.76 |
| ▸ | F10 | P00742 | 9/20 | 0.59 |
| ▸ | F2 | P00734 | 7/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396234 | 0.95 | F7 (0.74) | F7F3F10F2PRSS1 | |
| SCHEMBL6395317 | 0.94 | F7 (0.80) | F7F3F10F2PRSS1 | |
| SCHEMBL5527932 | 0.92 | F7 (0.72) | F7F3F10F2PRSS1 | |
| SCHEMBL5512942 | 0.86 | F7 (1.00) | F7F3F10F2PRSS1 | |
| SCHEMBL5571330 | 0.86 | F7 (0.73) | F7F3F10F2PRSS1 | |
| SCHEMBL13162282 | 0.86 | F7 (0.72) | F7F3F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL3463119 | 0.86 | F7 (0.72) | F7F3F10F2PRSS1 | |
| SCHEMBL3463836 | 0.84 | F7 (0.74) | F7F3F10F2PRSS1 | |
| SCHEMBL13162297 | 0.84 | F7 (0.70) | F7F3F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL3463027 | 0.84 | F7 (0.73) | F7F3F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919369-B2 | Controlling blood coagulation | GENENTECH, INC. (US) | 2005-07-19 | — | — | US | claimed |
| EP-1144373-B1 | SERINE PROTEASE INHIBITORS | GENENTECH INC (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1144373-A3 | SERINE PROTEASE INHIBITORS | Genentech, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1144373-A2 | SERINE PROTEASE INHIBITORS | Genentech, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000041531-A2 | SERINE PROTEASE INHIBITORS | GENENTECH, INC. (US) | 2000-07-20 | — | — | WO | disclosed |