Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398498 | 0.93 | PLA2G4B (0.50) | TSHRPLA2G4BSMPD1THRBGPBAR1 | |
| SCHEMBL6404654 | 0.90 | TSHR (0.59) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL6403931 | 0.87 | TSHR (0.63) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL6677146 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL17138159 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL16699620 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL3905859 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL4208924 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL17138169 | 0.86 | TSHR (0.76) | TSHRPLA2G4BSMPD1GGPS1THRA | |
| SCHEMBL27882949 | 0.84 | PLA2G4B (0.46) | TSHRPLA2G4BSMPD1THRBGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1454921-B1 | RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE | TOKUYAMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-20050009946-A1 | Radical polymerization catalyst and adhesive kit for dental use | TOKUYAMA CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1454921-A1 | RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE | Tokuyama Corporation (JP) | 2004-09-08 | — | — | EP | disclosed |