⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483135 | 0.81 | HDAC1 (0.31) | — | |
| SCHEMBL6813444 | 0.81 | HDAC1 (0.31) | — | |
| SCHEMBL3928699 | 0.80 | HDAC1 (0.30) | — | |
| SCHEMBL20916878 | 0.76 | HDAC6 (0.38) | — | |
| SCHEMBL991813 | 0.73 | HDAC1 (0.36) | — | |
| SCHEMBL15285910 | 0.73 | — | — | |
| SCHEMBL7856537 | 0.73 | HDAC6 (0.33) | — | |
| SCHEMBL25597697 | 0.73 | — | — | |
| SCHEMBL8169564 | 0.72 | HDAC6 (0.31) | — | |
| SCHEMBL8670355 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032789-A1 | Novel compounds useful in pain management | ASTRAZENECA CANADA INC. | 2005-02-10 | — | — | US | claimed |
| EP-1089965-B1 | Urea derivatives for pain management | ASTRAZENECA AB (SE) | 2004-09-15 | — | — | EP | claimed |
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | claimed |
| EP-1089967-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-04-11 | — | — | EP | claimed |
| EP-1089966-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-04-11 | — | — | EP | claimed |
| EP-1089965-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-04-11 | — | — | EP | claimed |
| EP-1087940-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067204-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | claimed |
| WO-1999067206-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | claimed |
| WO-1999067203-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | claimed |
| WO-1999067205-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | claimed |
| US-20050032789-A1 | Novel compounds useful in pain management | ASTRAZENECA CANADA INC. | 2005-02-10 | — | — | US | disclosed |
| EP-1089965-B1 | Urea derivatives for pain management | ASTRAZENECA AB (SE) | 2004-09-15 | — | — | EP | disclosed |
| US-6777561-B1 | MANAGEMENT OF PAIN; PHENYL-UREA COMPOUNDS | ASTRAZENECA CANADA INC. (CA) | 2004-08-17 | — | — | US | disclosed |
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |
| EP-1087940-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999067204-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067203-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067206-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067205-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |