SCHEMBL640352

SCHEMBL640352

O=C1CC=CSN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899793 0.83
SCHEMBL3114602 0.72
SCHEMBL5390716 0.61
SCHEMBL14315764 0.57 CRBN (0.42)
SCHEMBL5894794 0.56
SCHEMBL4751281 0.56
SCHEMBL2920862 0.56
SCHEMBL8874187 0.55
SCHEMBL828805 0.53
SCHEMBL7211064 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4103278-A1 SMALL MOLECULE STING ANTAGONISTS Curadev Pharma Pvt. Ltd. (IN) 2022-12-21 EP claimed
CN-114401969-A Heterocyclic compounds 豪夫迈·罗氏有限公司 2022-04-26 CN claimed
CN-104370853-B GSK-3 beta inhibitor or its salt and medicinal usage thereof 复旦大学 2016-08-10 CN claimed
CN-104370853-A GSK-3beta inhibitor or its salt and medicine application thereof UNIV FUDAN 2015-02-25 CN claimed
CN-101365696-A Compounds and compositions as modulators of steroid hormone nuclear receptors IRM LLC (BM) 2009-02-11 CN claimed
CN-1635891-A Tetrahydroquinoline analogues as muscarinic agonists ACADIA PHARM INC (US) 2005-07-06 CN claimed
EP-1537123-A1 COMPOUNDS GLAXO GROUP LIMITED (GB) 2005-06-08 EP claimed
WO-2004002992-A1 COMPOUNDS GLAXO GROUP LIMITED (GB) 2004-01-08 WO claimed
US-12006289-B2 Potassium channel inhibitors SANIONA A/S (DK) 2024-06-11 US disclosed
CN-113631538-B Novel potassium channel inhibitors 萨尼奥纳有限责任公司 2024-05-31 CN disclosed
CN-110494555-B Generation of lung bud organoids with branched structures and use thereof for modeling lung disease 纽约市哥伦比亚大学理事会 2024-04-02 CN disclosed
WO-2024050513-A1 PHENOTHIAZINES FOR TREATING MITOCHONDRIAL DISEASE ACUREX BIOSCIENCES CORPORATION (US) 2024-03-07 WO disclosed
US-20240034717-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA A/S (DK) 2024-02-01 US disclosed
CN-112218862-B Oxazolidinone antibiotic compounds and process for preparing same 巴格沃克斯研究有限公司 2024-01-02 CN disclosed
EP-0149297-A1 Process for preparing 3H-Phenothlazin-3-ones MERCK FROSST CANADA INC. (CA) 1985-07-24 EP disclosed
EP-0047164-B1 PROCESS FOR PREPARING 3-CHLORO-6-(2-HYDROXYPHENYL)-PYRIDAZINES SMITHKLINE BECKMAN CORPORATION (US) 1985-03-27 EP disclosed
US-4340733-A Process for preparing 3-chloro-6-(2-hydroxyphenyl)-pyridazines SMITHKLINE CORPORATION (US) 1982-07-20 US disclosed
EP-0047164-A2 Process for preparing 3-chloro-6-(2-hydroxyphenyl)-pyridazines SMITHKLINE BECKMAN CORPORATION (US) 1982-03-10 EP disclosed
US-4259498-A Process for preparing benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1981-03-31 US disclosed
US-4191689-A Benzisothiazole-1,1-dioxide and naphtho-1,2-thiazine-1,1-dioxide compounds POLAROID CORPORATION (US) 1980-03-04 US disclosed