SCHEMBL6403681

SCHEMBL6403681

CC1C(=O)N(NC(=O)[C@@H](NC(=O)C(N)c2cc(F)cc(F)c2)C(C)C)c2ccccc2-c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 20/20 0.47
PSEN2 P49810 20/20 0.47
APH1B Q8WW43 20/20 0.47
NCSTN Q92542 20/20 0.47
APH1A Q96BI3 20/20 0.47
PSENEN Q9NZ42 20/20 0.47
SPPL2A Q8TCT8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4424688 0.90 PSEN1 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4425826 0.84 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4420734 0.82 PSEN1 (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4413848 0.81 PSEN1 (0.66) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7431542 0.81 PSEN1 (0.66) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4411865 0.81 PSEN1 (0.66) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4414541 0.79 PSEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4424166 0.78 PSEN1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6307501 0.78 PSEN1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4413546 0.78 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1493728-B Sewing machine and shuttle for sewing machine BROTHER IND LTD 2012-09-05 CN disclosed
CN-1678137-A Inductive heating roller device and image forming device HARISON TOSHIBA LIGHTING CORP (JP) 2005-10-05 CN disclosed
US-6933479-B2 Induction heating roller apparatus and image formation apparatus HARISON TOSHIBA LIGHTING CORP. (JP) 2005-08-23 US disclosed
CN-1198184-C Induction hot roller device of imaging equipment HALEISEI TOSHIBA LIGHTING CO L (JP) 2005-04-20 CN disclosed
CN-1599516-A Induction warm-up mill,fixing device and image forming device HARLEYSHENG TOSHIBA LIGHTING & (JP) 2005-03-23 CN disclosed
US-6850728-B2 Induction heating roller apparatus, fixing apparatus and image formation apparatus HARISON TOSHIBA LIGHTING CORP. (JP) 2005-02-01 US disclosed
CN-1493728-A Sewing machine and shuttle for sewing machine 兄弟工业株式会社 2004-05-05 CN disclosed
US-20040005176-A1 Induction heating roller apparatus, fixing apparatus and image formation apparatus HARISON TOSHIBA LIGHTING CORP. (JP) 2004-01-08 US disclosed
US-20030213799-A1 Induction heating roller apparatus and image formation apparatus HARISON TOSHIBA LIGHTING CORP. (JP) 2003-11-20 US disclosed
CN-1452436-A Induction heating roller device, fixing device and image forming device HALISHEN TOSHIBA LIGHTING CO L (JP) 2003-10-29 CN disclosed
US-6573485-B2 Induction heating roller apparatus of image formation apparatus HARISON TOSHIBA LIGHTING CORP. (JP) 2003-06-03 US disclosed
CN-1396495-A Induction hot roller device of imaging equipment HALEISEI TOSHIBA LIGHTING CO L (JP) 2003-02-12 CN disclosed
US-20030000943-A1 Induction heating roller apparatus of image formation apparatus HARISON TOSHIBA LIGHTING CORP. 2003-01-02 US disclosed