Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712635 | 0.87 | CHEK1 (0.60) | CHEK1 | |
| SCHEMBL4880334 | 0.86 | CHEK1 (0.67) | CHEK1 | |
| SCHEMBL4883218 | 0.86 | CHEK1 (0.67) | CHEK1 | |
| SCHEMBL16712625 | 0.86 | CHEK1 (0.71) | CHEK1 | |
| SCHEMBL4886328 | 0.85 | CHEK1 (0.67) | CHEK1 | |
| SCHEMBL6412953 | 0.84 | CHEK1 (0.61) | CHEK1 | |
| SCHEMBL4887243 | 0.84 | CHEK1 (0.63) | CHEK1 | |
| SCHEMBL4856062 | 0.82 | CHEK1 (0.68) | CHEK1 | |
| SCHEMBL4882823 | 0.82 | CHEK1 (0.65) | CHEK1 | |
| SCHEMBL4889201 | 0.82 | CHEK1 (0.63) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606268-A1 | HETEROCYCLIC KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | claimed |
| WO-2004076424-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | claimed |