SCHEMBL6403994

SCHEMBL6403994

O=CCCCOC(=O)/C=C\C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 12/20 0.63
MAPT P10636 2/20 0.50
ATM Q13315 1/20 0.50
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 4/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
HIF1A Q16665 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6404001 1.00 HCAR2 (0.63) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL7763373 0.92 ATM (0.58) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL27670904 0.85 HCAR2 (0.76) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL2790619 0.85 HCAR2 (0.80) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL9150506 0.85 HCAR2 (0.76) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL8731689 0.85 HCAR2 (0.80) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL29220141 0.84 HCAR2 (0.63) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL9860583 0.84 HCAR2 (0.63) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL11411625 0.83 HCAR2 (0.81) HCAR2MAPTATMRAB9ANPSR1
SCHEMBL28266592 0.83 HCAR2 (0.81) HCAR2MAPTATMRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4348075-A1 POWER TRANSMISSION BELT Dayco Europe S.R.L. (IT) 2024-04-10 EP disclosed
US-6939601-B2 obtained by applying an unpigmented intermediate coat to a substrate to be coated,crosslinking the intermediate coat and forming an intermediate coat layer,applying an unpigmented top-coat , crosslinking; flexibility; automobiles BOLLIG & KEMPER GMBH & CO. KG (DE) 2005-09-06 US disclosed
US-20040121160-A1 obtainable by applying unpigmented intermediate coat to substrate to be coated, crosslinking intermediate coat, applying unpigmented top-coat to intermediate coat layer, crosslinking top coat; automobiles; impact resistance, gloss PPG COATINGS DEUTSCHLAND GMBH (DE) 2004-06-24 US disclosed
EP-1093498-A1 METHOD FOR IMPROVING APPEARANCE IN COMPOSITE COLOR-PLUS-CLEAR COATINGS, AND COMPOSITIONS FOR USE THEREIN BASF CORPORATION (US) 2001-04-25 EP disclosed
WO-1999057213-A1 METHOD FOR IMPROVING APPEARANCE IN COMPOSITE COLOR-PLUS-CLEAR COATINGS, AND COMPOSITIONS FOR USE THEREIN BASF CORPORATION (DE) 1999-11-11 WO disclosed
EP-0545947-A4 PROCESS FOR MAKING ETHANOL SOLUTIONS OF ALKYL HALF-ESTERS OF COPOLYMERS OF MALEIC ANHYDRIDE AND A C 1?-C 4? ALKYL VINYL ETHER 1993-07-21 EP disclosed
EP-0545947-A1 PROCESS FOR MAKING ETHANOL SOLUTIONS OF ALKYL HALF-ESTERS OF COPOLYMERS OF MALEIC ANHYDRIDE AND A C 1?-C 4? ALKYL VINYL ETHER. ISP INVESTMENTS INC (US) 1993-06-16 EP disclosed
WO-1992004405-A1 PROCESS FOR MAKING ETHANOL SOLUTIONS OF ALKYL HALF-ESTERS OF COPOLYMERS OF MALEIC ANHYDRIDE AND A C1-C4 ALKYL VINYL ETHER ISP INVESTMENTS INC. (US) 1992-03-19 WO disclosed