SCHEMBL6404199

SCHEMBL6404199

O=C(ON1C(=O)CCC1=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 17/20 0.51
ITGA4 P13612 17/20 0.51
ITGB7 P26010 1/20 0.47
HCRTR1 O43613 1/20 0.46
HCRTR2 O43614 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3901904 0.81 ITGB1 (0.59) ITGB1ITGA4ITGB7HCRTR1HCRTR2
SCHEMBL3901901 0.81 ITGB1 (0.59) ITGB1ITGA4ITGB7HCRTR1HCRTR2
SCHEMBL3904073 0.78 ITGB1 (0.67) ITGB1ITGA4ITGB7
SCHEMBL3904078 0.78 ITGB1 (0.67) ITGB1ITGA4ITGB7
SCHEMBL6150572 0.77 ITGB1 (0.56) ITGB1ITGA4ITGB7
SCHEMBL6150568 0.77 ITGB1 (0.56) ITGB1ITGA4ITGB7
SCHEMBL2988718 0.74 ITGB1 (0.66) ITGB1ITGA4ITGB7
SCHEMBL2988722 0.74 ITGB1 (0.66) ITGB1ITGA4ITGB7
SCHEMBL29575786 0.74 ITGB1 (0.65) ITGB1ITGA4ITGB7HCRTR1HCRTR2
SCHEMBL5201278 0.71 ITGB1 (0.58) ITGB1ITGA4ITGB7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846874-B2 An addition-condensation copolymer consisting of a polyolefin backbone and polyamide graft through an unsaturated monomer chosen from carboxylic acids, anhydrides, epoxides; processing around 180 degrees Celsius ARKEMA (FR) 2005-01-25 US disclosed
US-20040024127-A1 An addition-condensation copolymer consisting of a polyolefin backbone and polyamide graft through an unsaturated monomer chosen from carboxylic acids, anhydrides, epoxides; processing around 180 degrees Celsius ATOFINA (FR) 2004-02-05 US disclosed