Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195088 | 0.80 | CYP19A1 (0.53) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL1439686 | 0.76 | CYP19A1 (0.50) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL1439304 | 0.76 | CYP19A1 (0.50) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL19050813 | 0.76 | CYP19A1 (0.61) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL18503895 | 0.76 | CYP19A1 (0.61) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL17213209 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL4597731 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL4598002 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL17213197 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP17A1TDP1SIGMAR1SCN1A | |
| SCHEMBL4586180 | 0.75 | CYP19A1 (0.42) | CYP19A1CYP17A1TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043353-A1 | Cinchona-alkaloid-based catalysts, and asymmetric alcoholysis of cyclic anhydrides using them | BRANDEIS UNIVERSITY | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043353-A1 | Cinchona-alkaloid-based catalysts, and asymmetric alcoholysis of cyclic anhydrides using them | CA7, CA9, CA1 | CYP19A1 1119/4885CYP17A1 135/4885TDP1 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.