SCHEMBL6406735

SCHEMBL6406735

CCCCCC=C1C(=O)OC=C1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.39
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
TYR P14679 2/20 0.38
TRPV1 Q8NER1 2/20 0.38
ABHD16A O95870 1/20 0.38
TSHR P16473 1/20 0.36
FAAH O00519 4/20 0.35
MGLL Q99685 3/20 0.35
PRKCA P17252 5/20 0.33
PRKD3 O94806 2/20 0.33
PRKCG P05129 2/20 0.33
PRKCB P05771 2/20 0.33
PRKCH P24723 2/20 0.33
PRKCE Q02156 2/20 0.33
PRKCQ Q04759 2/20 0.33
PRKCD Q05655 2/20 0.33
PRKD1 Q15139 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26089455 0.72 TYR (0.50) PPARGNFKB1NFKB2RELATYR
SCHEMBL27580145 0.72 TYR (0.50) PPARGNFKB1NFKB2RELATYR
SCHEMBL27572070 0.72 TYR (0.50) PPARGNFKB1NFKB2RELATYR
SCHEMBL27636950 0.72 TYR (0.50) PPARGNFKB1NFKB2RELATYR
SCHEMBL27825897 0.72 TYR (0.50) PPARGNFKB1NFKB2RELATYR
SCHEMBL9533245 0.69 KMT2A (0.42) PPARGTYRTSHR
SCHEMBL9533250 0.69 KMT2A (0.42) PPARGTYRTSHR
SCHEMBL9529501 0.68 KMT2A (0.41) PPARGTYRTRPV1ABHD16ATSHR
SCHEMBL9529497 0.68 KMT2A (0.41) PPARGTYRTRPV1ABHD16ATSHR
SCHEMBL29029409 0.67 TSHR (0.44) PPARGNFKB1NFKB2RELATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed