⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23394524 | 1.00 | — | — | |
| SCHEMBL15591639 | 1.00 | — | — | |
| SCHEMBL7731926 | 0.87 | — | — | |
| SCHEMBL9907097 | 0.80 | — | — | |
| SCHEMBL13612915 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL25302707 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL25258352 | 0.74 | — | — | |
| SCHEMBL24908762 | 0.70 | — | — | |
| SCHEMBL11878621 | 0.70 | — | — | |
| SCHEMBL17675791 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-20230002412-A1 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. | 2023-01-05 | — | — | US | disclosed |
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| EP-3492464-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Sciences, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018093577-A1 | CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2017-10-12 | — | — | US | disclosed |
| EP-3006444-B1 | HETEROCYCLIC AMIDE COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2017-09-27 | — | — | EP | disclosed |
| US-9708314-B2 | Heterocyclic amide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| US-9708314-B2 | Heterocyclic amide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| WO-2008012180-A1 | FUSED NAPHTHALENES | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |
| US-20050053552-A1 | Phase shift colloids as ultrasound contrast agents | QUAY STEVEN C (US) | 2005-03-10 | — | — | US | disclosed |
| US-6569404-B1 | Aqueous colloidal suspension, dispersed phase is gas microbubbles of perfluoropropane, perfluorobutane, perfluoropentane, perfluorohexane or sulfur hexafluoride; fluorinated amphiphile for stabilizing microbubbles | AMERSHAM HEALTH A/S (NO) | 2003-05-27 | — | — | US | disclosed |
| US-6245319-B1 | Colloidal dispersions of perfluoropentane | SONUS PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| EP-0680341-B1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMA INC (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-1038535-A2 | Use of selected perfluorocarbons for the preparation of diagnostic ultrasound contrast agents | SONUS PHARMACEUTICALS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| US-5876696-A | Composition comprising a fluorine containing surfactant and perfluoropentane for ultrasound | SONUS PHARMACEUTICALS, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5558853-A | WATER IMMISCIBLE FLUORINE COMPOUND | SONUS PHARMACEUTICALS (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0680341-A1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMACEUTICALS, INC. (US) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994016739-A1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMACEUTICALS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |