Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.90 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194401 | 1.00 | TSHR (0.90) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| Sebacic Acid SCHEMBL10956921 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| SCHEMBL3502474 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| Adipic Acid SCHEMBL3799583 | 0.97 | TSHR (0.95) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| SCHEMBL905415 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| Adipic Acid SCHEMBL10792220 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| SCHEMBL3504014 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| SCHEMBL3504444 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| SCHEMBL3503428 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 | |
| Sebacic Acid SCHEMBL10962129 | 0.97 | TSHR (0.86) | TSHRLMNAALDH1A1NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263797-A | Reactive distillation and purification method for preparing dimethyl adipate | 唐山中溶科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-1802330-A | Cement dispersant and concrete composition containing the dispersant | SIKA LTD (JP) | 2006-07-12 | — | — | CN | disclosed |
| CN-1777565-A | Cement dispersing agent and concrete composition comprising same | NIPPON SEQUA K K (JP) | 2006-05-24 | — | — | CN | disclosed |
| WO-2005037426-A1 | CONICAL GAS / LIQUID SEPARATOR WITH A STIRRER FOR MAKING A GREASE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| CN-1225919-A | Synthesizing method for dimethyl ester of mixed acid of butane diacid, glutaric acid and hexane diacid | YUEYANG PETRO CHEMICAL GENERAL (CN) | 1999-08-18 | — | — | CN | disclosed |