SCHEMBL6408747

SCHEMBL6408747

CCC(C)N=C=O.O=C=Nc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TSHR P16473 2/20 0.40
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
MIF P14174 4/20 0.35
TRPA1 O75762 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL28810205 0.81 CYP3A4 (0.52) CYP3A4TSHRGABRA1GABRB2MIF
SCHEMBL18479689 0.80 MIF (0.39) TSHRMIFTRPA1TRPV1LMNA
Butane SCHEMBL27642284 0.79 CYP3A4 (0.50) CYP3A4TSHRGABRA1GABRB2MIF
SCHEMBL27282865 0.79 CYP3A4 (0.50) CYP3A4TSHRGABRA1GABRB2MIF
Trimethylammonium SCHEMBL27447810 0.77 CYP3A4 (0.46) CYP3A4TSHRGABRA1GABRB2MIF
Ethane SCHEMBL6323027 0.77 CYP3A4 (0.50) CYP3A4TSHRGABRA1GABRB2MIF
SCHEMBL5925 0.77
SCHEMBL1332539 0.77
SCHEMBL245090 0.77 MIF (0.55) CYP3A4TSHRGABRA1GABRB2MIF
SCHEMBL220893 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050171302-A1 Coating composition for tendon for prestressed concrete SHINKO WIRE CO., LTD. (JP) 2005-08-04 US disclosed