Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409116 | 1.00 | PPARG (0.40) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL6409120 | 1.00 | PPARG (0.40) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL6130440 | 1.00 | PPARG (0.40) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL7799168 | 0.98 | PPARG (0.42) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL7171969 | 0.98 | PPARG (0.42) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL7799171 | 0.98 | PPARG (0.42) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL7171967 | 0.98 | PPARG (0.42) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL7171974 | 0.98 | PPARG (0.42) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL8332550 | 0.93 | FFAR1 (0.40) | PPARGGPR132ALDH1A1TSHRFFAR1 | |
| SCHEMBL8332552 | 0.93 | FFAR1 (0.40) | PPARGGPR132ALDH1A1TSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059090-A1 | Method of screening non-peptide, non-steroid invertebrate pheromone compounds having mitogen-activated protein kinase modulating activity and compositions containing the same | ZAMIR NADAV (IL) | 2005-03-17 | — | — | US | claimed |
| US-6806293-B1 | SREENING FOR MITOGEN ACTIVATED PROTEIN (MAP) INTERACTION | DARLEY PHARMACEUTICALS LTD (IL) | 2004-10-19 | — | — | US | claimed |
| US-20050059090-A1 | Method of screening non-peptide, non-steroid invertebrate pheromone compounds having mitogen-activated protein kinase modulating activity and compositions containing the same | ZAMIR NADAV (IL) | 2005-03-17 | — | — | US | disclosed |
| US-6806293-B1 | SREENING FOR MITOGEN ACTIVATED PROTEIN (MAP) INTERACTION | DARLEY PHARMACEUTICALS LTD (IL) | 2004-10-19 | — | — | US | disclosed |