Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6411940 | 0.91 | CCR8 (0.59) | CCR8 | |
| SCHEMBL4371729 | 0.88 | CCR8 (0.64) | CCR8 | |
| SCHEMBL6437668 | 0.87 | CCR8 (0.55) | CCR8 | |
| SCHEMBL6361502 | 0.87 | CCR8 (0.55) | CCR8 | |
| SCHEMBL6206397 | 0.87 | CCR8 (0.55) | CCR8 | |
| SCHEMBL6249952 | 0.86 | CCR8 (0.48) | CCR8 | |
| SCHEMBL6204086 | 0.85 | CCR8 (0.52) | CCR8 | |
| SCHEMBL4952716 | 0.83 | CCR8 (0.54) | CCR8 | |
| SCHEMBL6204820 | 0.82 | CCR8 (0.60) | CCR8 | |
| SCHEMBL6204708 | 0.81 | CCR8 (0.48) | CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581511-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058736-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |