Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404365 | 0.79 | GRK6 (0.40) | GRK6WNT3ATNKS2NISCHSCN10A | |
| SCHEMBL6409060 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2E1CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6408622 | 0.78 | GRK6 (0.62) | GRK6SCN10ASCN9A | |
| SCHEMBL6404070 | 0.77 | SCN9A (0.49) | GRK6SCN10ASCN9AMAOB | |
| SCHEMBL16171132 | 0.77 | GRK6 (0.49) | GRK6SCN10AKCNH2SCN9ASCN1A | |
| SCHEMBL6405768 | 0.76 | GRK6 (0.38) | GRK6WNT3ATNKS2NISCHSCN10A | |
| SCHEMBL6411081 | 0.72 | SCN9A (0.47) | GRK6CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL25260119 | 0.71 | SCN10A (0.47) | GRK6WNT3ATNKS2NISCHSCN10A | |
| SCHEMBL6406665 | 0.70 | NPY5R (0.42) | CYP1A2CYP3A4NPY5RKDM1AMAOB | |
| SCHEMBL10171990 | 0.69 | SCN10A (0.45) | GRK6WNT3ATNKS2NISCHSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | GRK6 3937/4885CYP1A2 93/4885CYP2E1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.