SCHEMBL641218

SCHEMBL641218

CCCN(Cc1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.70
CYP2C19 P33261 1/20 0.57
CNR2 P34972 3/20 0.53
NR1H2 P55055 2/20 0.51
NR1H3 Q13133 2/20 0.51
CYP2D6 P10635 2/20 0.49
LMNA P02545 2/20 0.47
GLA P06280 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 1/20 0.46
TAAR1 Q96RJ0 2/20 0.45
CYP1A2 P05177 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
PDE6A P16499 1/20 0.45
ADRA2C P18825 1/20 0.45
MC4R P32245 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11824339 0.89 CYP2C19 (0.76) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL11535130 0.89 TSHR (0.56) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL627791 0.88 TSHR (0.66) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL24405420 0.87 TSHR (0.55) TSHRCYP2C19CNR2NR1H2NR1H3
Butane SCHEMBL28032421 0.87 TSHR (0.76) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL8092493 0.86 TSHR (0.63) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL16329012 0.85 TSHR (0.61) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL7762911 0.85 TSHR (0.61) TSHRCYP2C19CNR2NR1H2NR1H3
SCHEMBL20871451 0.84 CNR2 (0.53) TSHRCYP2C19CNR2CYP2D6LMNA
SCHEMBL11691631 0.84 TSHR (0.51) TSHRCYP2C19NR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3004286-B1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS CYALUME TECH INC (US) 2019-08-28 EP claimed
US-9115305-B2 Broad temperature performance chemiluminescent systems and methods CYALUME TECHNOLOGIES, INC. (US) 2015-08-25 US claimed
US-20140353559-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 US claimed
US-20140356975-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US claimed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US claimed
US-12077631-B2 Bulk polymerisation of polyoxazolidone BASF SE (DE) 2024-09-03 US disclosed
CN-112424253-B Bulk polymerization of polyoxazolidinones 巴斯夫欧洲公司 2024-02-27 CN disclosed
EP-3824012-B1 BULK POLYMERISATION OF POLYOXAZOLIDONE BASF SE (DE) 2022-09-07 EP disclosed
CN-110300772-B Polyoxazolidinones and process for their preparation 巴斯夫欧洲公司 2022-04-26 CN disclosed
US-11180603-B2 Polyoxazolidones and production thereof BASF SE (DE) 2021-11-23 US disclosed
US-20210253782-A1 BULK POLYMERISATION OF POLYOXAZOLIDONE BASF SE (DE) 2021-08-19 US disclosed
EP-3583148-B1 POLYOXAZOLIDONES AND PRODUCTION OF THE SAME BASF SE (DE) 2021-03-03 EP disclosed
US-4322352-A Indolyl phthalide compounds STERLING DRUG INC. (US) 1982-03-30 US disclosed
US-4307018-A CHROMOGENS FOR COPYING SYSTEMS STERLING DRUG INC. (US) 1981-12-22 US disclosed
US-4257954-A INDOLYL-PHENYLSULFONYL-PHENYL METHANE STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4251446-A COLOR PRECURSORS STERLING DRUG INC. (US) 1981-02-17 US disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed
US-4189171-A PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS STERLING DRUG INC. (US) 1980-02-19 US disclosed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US disclosed
US-4059402-A SUBLIMATION, MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed