Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869211 | 0.80 | KDM4E (0.37) | LMNATSHRNFKB1 | |
| SCHEMBL18902615 | 0.78 | MCL1 (0.34) | LMNA | |
| SCHEMBL25660993 | 0.77 | SMN1; SMN2 (0.55) | FOLH1 | |
| SCHEMBL4787354 | 0.77 | FOLH1 (0.40) | ECE1FOLH1HDAC3HDAC1HDAC2 | |
| SCHEMBL153514 | 0.75 | MCL1 (0.39) | — | |
| SCHEMBL27813271 | 0.73 | ECE1 (0.47) | ECE1FOLH1CA2LMNACYP3A4 | |
| SCHEMBL3056738 | 0.73 | — | — | |
| SCHEMBL18902875 | 0.73 | — | — | |
| SCHEMBL158299 | 0.73 | — | — | |
| SCHEMBL9781760 | 0.72 | CXCR1 (0.37) | ECE1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539953-A2 | PROXIMITY-AIDED SYNTHESIS OF TEMPLATED MOLECULES | Nuevolution A/S (DK) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024929-A2 | PROXIMITY-AIDED SYNTHESIS OF TEMPLATED MOLECULES | NUEVOLUTION A/S (DK) | 2004-03-25 | — | — | WO | disclosed |